SS-31

Key Functions & Benefits

• Improved Mitochondrial Function and Energy: SS-31 penetrates cells and accumulates on the inner mitochondrial membrane, where it binds to cardiolipin, preventing its oxidation and protecting mitochondrial structure. This stabilizes the mitochondrial structure, restores ATP synthesis, and reduces electron leakage, leading to increased cellular energy.
• Anti-Aging and Longevity Potential: Studies show that SS-31 can reverse age-related declines in mitochondrial ATP production, reduce cellular senescence, and improve cardiac diastolic function in older subjects. It has been shown to reduce frailty markers and boost muscle mass and fatigue resistance in aged models.
• Enhanced Muscle Performance: In studies with aged mice, eight weeks of SS-31 treatment significantly increased treadmill endurance, restored redox homeostasis, and improved skeletal muscle mitochondrial quality.
• Neuroprotection and Cognitive Health: Preclinical research indicates that SS-31 offers significant neuroprotection in models of Alzheimer’s, Parkinson’s, and traumatic brain injury (TBI). It helps maintain synaptic health, reduces neuroinflammation, and improves cognitive function.
• Cardiovascular Protection: SS-31 has shown promise in reducing ischemia-reperfusion injury, improving cardiac output, and reducing the formation of plaque-forming foam cells.
• Reduction of Oxidative Stress and Inflammation: By reducing mitochondrial-derived ROS and inhibiting the inflammatory response, SS-31 protects against various diseases, including diabetes and retinal disease.