
Key Functions & Benefits
- Mechanism: Inhibits NNMT, which helps reverse metabolic dysfunction and prevents the accumulation of adipose tissue.
- Benefits: Studied for weight loss (fat reduction), enhanced muscle repair/regeneration, and increased metabolic efficiency
- Research Areas: Primarily used in studies related to obesity, muscle injury, and longevity.
- NNMT Inhibition: NNMT is an enzyme found in fat cells that, when overactive, slows metabolism and increases fat storage.
- NAD+ Preservation: By blocking NNMT, the compound prevents the depletion of NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme for cellular energy production.
- SIRT1 Activation: Increased NAD+ levels activate the SIRT1 “longevity gene,” which improves insulin sensitivity and mitochondrial function.