HUMANIN – 10mg

Key Functions & Benefits

• Origin: Encoded by the mitochondrial genome (16S ribosomal RNA gene, MT-RNR2).
• Neuroprotection: It was initially identified for its ability to protect neurons from amyloid-beta induced cell death (Alzheimer’s).
• Disease Resistance: Humanin acts as a stress-response molecule that is protective against Alzheimer’s, strokes, atherosclerosis, and myocardial infarction.
• Metabolic Effects: It improves glucose metabolism and insulin sensitivity in animal models, showing potential in treating obesity and type 2 diabetes.
• Aging & Lifespan: Levels of humanin in the blood correlate with lifespan in various mouse models, and its levels are higher in the children of supercentenarians.
• Signaling Mechanism: Humanin acts through the GP130/1L6ST receptor complex to activate protective pathways like AKT,, ERK1/2 and STAT3.